| Caloric restriction with or without exercise: the fitness versus fatness debate. | |
| | |
MedLine Citation:
|
PMID: 20010118 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To determine whether a 25% energy deficit that produces equal change in body fatness leads to greater cardiometabolic benefits when aerobic exercise is included. METHODS: Thirty-six overweight participants (16 males/20 females) (39 +/- 1 yr; 82 +/- 2 kg; body mass index = 27.8 +/- 0.3 kg x m2, mean +/- SEM) were randomized to one of three groups (n = 12 for each) for a 6-month intervention: control (CO, weight-maintenance diet), caloric restriction (CR, 25% reduction in energy intake), or caloric restriction plus aerobic exercise (CR + EX, 12.5% reduction in energy intake plus 12.5% increase in exercise energy expenditure). Food was provided during weeks 1-12 and 22-24. Changes in fat mass, visceral fat, VO2peak (graded treadmill test), muscular strength (isokinetic knee extension/flexion), blood lipids, blood pressure, and insulin sensitivity/secretion were compared. RESULTS: As expected, VO2peak was significantly improved after 6 months of intervention in CR + EX only (22 +/- 5% vs 7 +/- 5% in CR and -5 +/- 3% in CO), whereas isokinetic muscular strength did not change. There was no difference in the losses of weight, fat mass, or visceral fat and changes in systolic blood pressure (BP) between the intervention groups. However, only CR + EX had a significant decrease in diastolic BP (-5 +/- 3% vs -2 +/- 2% in CR and -1 +/- 2% in CO), in low-density lipoprotein (LDL) cholesterol (-13 +/- 4% vs -6 +/- 3% in CR and 2 +/- 4% in CO), and a significant increase in insulin sensitivity (66 +/- 22% vs 40 +/- 20% in CR and 1 +/- 11% in CO). CONCLUSIONS: Despite similar effect on fat losses, combining CR with exercise increased aerobic fitness in parallel with improved insulin sensitivity, LDL cholesterol, and diastolic BP. The results lend support for inclusion of an exercise component in weight loss programs to improve metabolic fitness. |
| | |
Authors:
|
D Enette Larson-Meyer; Leanne Redman; Leonie K Heilbronn; Corby K Martin; Eric Ravussin |
Related Documents
:
|
21495078 - Interim follow-up of a randomized controlled trial comparing chinese style mind body (t... 21719448 - Relationship between peak cardiac pumping capability and selected exercise-derived prog... 10365988 - Physical exercise as a modulator of adaptation to low and high carbohydrate and low and... 22017618 - Study on factors influencing recrudescent time of postdischarge patients with chronic o... 7458078 - Ciliary beat frequency in human respiratory explants. 730598 - Effects of exercise, vitamin e, and ozone on pulmonary function and lipid peroxidation. |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Medicine and science in sports and exercise Volume: 42 ISSN: 1530-0315 ISO Abbreviation: Med Sci Sports Exerc Publication Date: 2010 Jan |
Date Detail:
|
Created Date: 2009-12-17 Completed Date: 2010-03-05 Revised Date: 2011-05-06 |
Medline Journal Info:
|
Nlm Unique ID: 8005433 Medline TA: Med Sci Sports Exerc Country: United States |
Other Details:
|
Languages: eng Pagination: 152-9 Citation Subset: IM; S |
Affiliation:
|
Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA. enette@uwyo.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Analysis of Variance Body Composition Caloric Restriction / methods* Energy Metabolism Exercise / physiology* Female Humans Lipids / blood Male Middle Aged Muscle Strength / physiology Overweight Oxygen Consumption / physiology Physical Fitness Treatment Outcome Weight Loss* |
| Grant Support | |
ID/Acronym/Agency:
|
K01 DK062018/DK/NIDDK NIH HHS; K01 DK062018-01/DK/NIDDK NIH HHS; K23 DK068052/DK/NIDDK NIH HHS; K23 DK068052-02/DK/NIDDK NIH HHS; U01 AG020478-01/AG/NIA NIH HHS; U01 AG20478/AG/NIA NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Lipids |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Spontaneous Pacing during Overground Hill Running.
Next Document: Ergogenic and antioxidant effects of spirulina supplementation in humans.