| Calmodulin, cell growth and gene expression. | |
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MedLine Citation:
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PMID: 2479144 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Calmodulin is thought to regulate a number of intracellular processes, including cell proliferation. Previous studies using drugs that antagonize calmodulin function have indicated that calmodulin is required for progression at specific points in the eukaryotic cell cycle. However, interpretation of these results has previously been difficult due to the lack of specificity of these inhibitors in living cells. Recent studies have used a combination of molecular biological and genetic analysis techniques to approach the study of calmodulin-dependent cell cycle control with greater precision and specificity. These studies have confirmed that calmodulin is an important regulator of the cell cycle, and provide new ways in which to examine the cellular mechanisms involved in calmodulin-dependent cell cycle control. |
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Authors:
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C D Rasmussen; A R Means |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Trends in neurosciences Volume: 12 ISSN: 0166-2236 ISO Abbreviation: Trends Neurosci. Publication Date: 1989 Nov |
Date Detail:
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Created Date: 1989-12-21 Completed Date: 1989-12-21 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 7808616 Medline TA: Trends Neurosci Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 433-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Calmodulin / genetics, physiology* Cell Division / physiology* Cyclic AMP / metabolism Gene Expression / physiology* Genetic Vectors / physiology Growth Substances / physiology Maturation-Promoting Factor Microtubules / physiology |
| Chemical | |
Reg. No./Substance:
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0/Calmodulin; 0/Growth Substances; 60-92-4/Cyclic AMP; EC 2.7.11.22/Maturation-Promoting Factor |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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