Document Detail

Calibration of self-reported dietary measures using biomarkers: an approach to enhancing nutritional epidemiology reliability.
MedLine Citation:
PMID:  23881548     Owner:  NLM     Status:  MEDLINE    
Reports from nutritional epidemiology studies lack reliability if based solely on self-reported dietary consumption estimates. Consumption biomarkers are available for some components of diet. These can be collected in subsets of study cohorts, along with corresponding self-report assessments. Linear regression of (log-transformed) biomarker values on corresponding self-report values and other pertinent study subject characteristics yields calibration equations for dietary consumption, from which calibrated consumption estimates can be calculated throughout study cohorts. Nutritional epidemiology disease association studies of enhanced reliability can be expected from analyses that relate disease risk to calibrated consumption estimates. Applications to the study of energy and protein consumption in relation to cardiovascular diseases, type 2 diabetes, and cancer in the Women's Health Initiative will be briefly summarized. Also, challenges related to variables that may either mediate or confound associations of interest will be described, along with the need for longitudinal biomarker and self-report data, and the need for additional nutritional biomarker development.
Ross L Prentice; Lesley F Tinker; Ying Huang; Marian L Neuhouser
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current atherosclerosis reports     Volume:  15     ISSN:  1534-6242     ISO Abbreviation:  Curr Atheroscler Rep     Publication Date:  2013 Sep 
Date Detail:
Created Date:  2013-07-24     Completed Date:  2014-04-02     Revised Date:  2014-09-02    
Medline Journal Info:
Nlm Unique ID:  100897685     Medline TA:  Curr Atheroscler Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  353     Citation Subset:  IM    
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MeSH Terms
Biological Markers / analysis
Cardiovascular Diseases / epidemiology*
Energy Intake / physiology*
Nutrition Assessment
Reproducibility of Results
Grant Support
Reg. No./Substance:
0/Biological Markers

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