| Calculation of effective renal plasma flow using 125I-orthoiodohippuran: comparison of four methods. | |
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MedLine Citation:
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PMID: 4006326 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fifty-three determinations of effective renal plasma flow (ERPF) were made on 21 patients with a wide range of renal function. Serial plasma samples for 6 hours after the injection of 125I-orthoiodohippurate were used to plot the plasma disappearance curve, and a standard ERPF was calculated using biexponential analysis of the curve. ERPF values calculated by 3 published approximation methods using limited plasma samples were compared to the standard values. All approximation methods overestimated the ERPF, the mean percentage error lying between + 18.3% +/- 20.4% and + 70.0% +/- 51.3%. With 2 of the 3 approximation methods the overestimation was particularly prominent in patients with moderate to severe renal insufficiency (ERPF less than 300 ml/min). For research purposes the more accurate and reliable biexponential method of analysis of ERPF is recommended. |
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Authors:
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D J Taylor; P Griffiths; C P Swainson; R R Bailey; J G Turner |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Clinical nephrology Volume: 23 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 1985 Apr |
Date Detail:
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Created Date: 1985-08-09 Completed Date: 1985-08-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 169-72 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Humans Iodine Radioisotopes / diagnostic use Iodohippuric Acid / diagnostic use* Mathematics Methods Renal Circulation* Urodynamics |
| Chemical | |
Reg. No./Substance:
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0/Iodine Radioisotopes; 147-58-0/Iodohippuric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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