Document Detail

Calculating the maximum recommended dose of local anesthetic.
MedLine Citation:
PMID:  17269289     Owner:  NLM     Status:  MEDLINE    
Since patients have a wide variance in body size, it is appropriate to base the maximum recommended dose of a local anesthetic on a milligram of drug per kilogram of body weight. Other variables (severe overweight or underweight and cardiovascular compromise) also influence the appropriate maximum recommended dose. By calculating the specific dose limit from the maximum recommended dose for each patient, the chances of a local anesthetic overdose can be significantly reduced.
Joel M Weaver
Related Documents :
16675579 - A phase i study of a new nucleoside analogue, osi-7836, using two administration schedu...
18335219 - Cisplatin plus weekly cpt-11/docetaxel in advanced esophagogastric cancer: a phase i st...
8328409 - High-dose chlorambucil and dexamethasone for relapsed non-hodgkin's lymphomas.
8120919 - Irinotecan (cpt-11) high-dose escalation using intensive high-dose loperamide to contro...
16979839 - Phase i trial of cetuximab in combination with capecitabine, weekly irinotecan, and rad...
8490909 - A phase ii study of constant-infusion floxuridine for the treatment of metastatic renal...
977789 - A comparison of the bioavailability of digoxin in capsule, tablet, and solution taken o...
3936099 - Schedule-controlled behavior as an index of the development and loss of ethanol toleran...
25426579 - Abt-089, but not abt-107, ameliorates nicotine withdrawal-induced cognitive deficits in...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the California Dental Association     Volume:  35     ISSN:  1043-2256     ISO Abbreviation:  J Calif Dent Assoc     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-02-02     Completed Date:  2007-03-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8905668     Medline TA:  J Calif Dent Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  61-3     Citation Subset:  D    
Section of Oral and Maxillofacial Surgery, Pathology and Anesthesiology, Department of Anesthesiology, College of Medicine and Public Health, The Ohio State University, Columbus 43218, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anesthesia, Dental*
Anesthetics, Local / administration & dosage*,  poisoning
Body Weight*
Bupivacaine / administration & dosage
Drug Interactions
Epinephrine / administration & dosage
Lidocaine / administration & dosage
Mepivacaine / administration & dosage
Overdose / prevention & control
Time Factors
Vasoconstrictor Agents / administration & dosage
Reg. No./Substance:
0/Anesthetics, Local; 0/Vasoconstrictor Agents; 137-58-6/Lidocaine; 2180-92-9/Bupivacaine; 51-43-4/Epinephrine; 96-88-8/Mepivacaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Management of the hypertensive dental patient.
Next Document:  Health disparities and prevention: racial/ethnic barriers to flu vaccinations.