Document Detail


Calcium3D: a visual software package for the simulation of calcium buffered diffusion in neuroendocrine cells.
MedLine Citation:
PMID:  16199107     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We present Calcium3D, a user-friendly software package for simulating calcium triggered processes in neuroendocrine cells. We use Monte Carlo methods for the simulation of the basic processes involved: entry of calcium into the cytoplasm, the diffusion of ions and mobile intracellular calcium buffers inside the intracellular medium, and the kinetics of the reaction of calcium with these buffers. The outputs of the simulation are calcium and buffer concentrations as a function of time and for different depths from the cellular membrane.
Authors:
Germán Carrera; Amparo Gil; Javier Segura
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-09-30
Journal Detail:
Title:  Computer methods and programs in biomedicine     Volume:  80     ISSN:  0169-2607     ISO Abbreviation:  Comput Methods Programs Biomed     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-10-24     Completed Date:  2006-01-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8506513     Medline TA:  Comput Methods Programs Biomed     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  173-80     Citation Subset:  IM    
Affiliation:
Depto. de Matemáticas, Estadística y Computación, Universidad de Cantabria, 39005 Santander, Spain.
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MeSH Terms
Descriptor/Qualifier:
Calcium / metabolism*
Computer Graphics
Diffusion
Kinetics
Neurosecretory Systems / cytology,  metabolism*
Software*
Chemical
Reg. No./Substance:
7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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