| Calcium supplementation and prevention of pregnancy induced hypertension. | |
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MedLine Citation:
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PMID: 8987323 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a randomized controlled trial 201 healthy nulliparous women were randomly allocated by means of a computer generated randomization list. From 20 weeks of gestation until delivery they received either 2 g of oral elemental calcium (n = 103) per day or an identical placebo (n = 98). Eleven women (5.47%) were lost to follow-up after randomization. The study groups were very similar at the time of randomization; with respect to several clinical and demographic variables. Treatment compliance was very similar in both groups as was determined by pill count. The rate of pregnancy induced hypertension was lower in the calcium group than in the placebo group 8.24%; vs 29.03%; (RR = 0.28; 95% CI 0.14-0.59). The incidence of gestational hypertension was 6.18% in the calcium group and 17.20% in the placebo group (RR = 0.28; 95% CI 0.08-0.80), and the incidence of preeclampsia was 2.06% in the calcium group and 11.82% in the placebo group (RR = 0.13; 95% CI 0.01-0.64). In conclusion calcium supplementation given in pregnancy to nulliparous women reduces the incidence of pregnancy induced hypertension. |
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Authors:
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M Purwar; H Kulkarni; V Motghare; S Dhole |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: The journal of obstetrics and gynaecology research Volume: 22 ISSN: 1341-8076 ISO Abbreviation: J. Obstet. Gynaecol. Res. Publication Date: 1996 Oct |
Date Detail:
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Created Date: 1997-03-19 Completed Date: 1997-03-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9612761 Medline TA: J Obstet Gynaecol Res Country: JAPAN |
Other Details:
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Languages: eng Pagination: 425-30 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, Government Medical College, Nagpur, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Calcium
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administration & dosage,
therapeutic use* Double-Blind Method Female Humans Hypertension / prevention & control* Placebos Pre-Eclampsia / prevention & control Pregnancy Pregnancy Complications, Cardiovascular / prevention & control* Pregnancy Outcome Prospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Placebos; 7440-70-2/Calcium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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