Document Detail

Calcium nutrition and metabolism during infancy.
MedLine Citation:
PMID:  16831534     Owner:  NLM     Status:  MEDLINE    
Calcium is a vital mineral for the developing newborn infant. This review discusses perinatal and neonatal calcium metabolism, with an emphasis on enteral calcium absorption and the nutritional factors affecting calcium bioavailability including the three major endocrine hormones involved in calcium metabolism: parathyroid hormone, vitamin D, and calcitonin. The placenta transports calcium to the fetus throughout pregnancy, with the largest amount of fetal calcium accumulation occurring in the third trimester. At birth, the newborn transitions to intestinal absorption to meet the body's calcium needs. Most calcium is absorbed by paracellular passive diffusion in the small intestine. Calcium intestinal absorption is affected by the type and amount of calcium ingested. It is also affected by the amount of intestinal calcium that is bound to dietary fats and proteins. One major consequence of decreased calcium absorption is metabolic bone disease in which there is a failure of complete mineralization of the bone osteoid.
J Kirk Bass; Gary M Chan
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Publication Detail:
Type:  Journal Article; Review     Date:  2006-07-10
Journal Detail:
Title:  Nutrition (Burbank, Los Angeles County, Calif.)     Volume:  22     ISSN:  0899-9007     ISO Abbreviation:  Nutrition     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-10-09     Completed Date:  2007-01-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8802712     Medline TA:  Nutrition     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1057-66     Citation Subset:  IM    
Department of Pediatrics, Division of Neonatology, University of Utah Health Science Center, Salt Lake City, Utah, USA.
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MeSH Terms
Biological Availability
Calcification, Physiologic / physiology*
Calcitonin / metabolism
Calcium / metabolism*
Calcium, Dietary / administration & dosage*,  pharmacokinetics
Fetus / metabolism
Infant, Newborn / metabolism*
Intestinal Absorption
Nutritional Requirements
Parathyroid Hormone / metabolism
Phosphorus / metabolism
Placenta / metabolism*
Pregnancy / metabolism
Vitamin D / metabolism
Reg. No./Substance:
0/Calcium, Dietary; 0/Parathyroid Hormone; 1406-16-2/Vitamin D; 7440-70-2/Calcium; 7723-14-0/Phosphorus; 9007-12-9/Calcitonin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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