Document Detail


Calcium intake and blood pressure in elderly women.
MedLine Citation:
PMID:  1476146     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The authors studied the relative importance of calcium intake as a correlate of blood pressure in a cross-sectional analysis of 6,517 nonblack women aged > or = 65 years from Portland, Oregon; Minneapolis, Minnesota; Baltimore, Maryland; and the Monongahela Valley near Pittsburgh, Pennsylvania, who enrolled in the Study of Osteoporotic Fractures in 1986. Dietary calcium intake was measured by using a modified food frequency questionnaire. There were weak associations between total calcium intake and blood pressure, such that each 1,000 mg/day increase in calcium intake was associated with a 1.5 mmHg decrease in systolic blood pressure (95% confidence interval -2.2 to -0.8, p < 0.0001) and a 0.5 mmHg decrease in diastolic pressure (95% confidence interval -0.8 to -0.20, p < 0.004). After adjustment for confounding variables, total calcium intake continued to have a weak inverse association only with diastolic blood pressure. The multivariate models revealed several stronger independent risk factors for blood pressure, including age, body mass index, alcohol consumption, and level of education (all p < 0.01). The small size of the inverse association between calcium intake and blood pressure limits its biological importance in this population of elderly women.
Authors:
J A Simon; W S Browner; J L Tao; S B Hulley
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of epidemiology     Volume:  136     ISSN:  0002-9262     ISO Abbreviation:  Am. J. Epidemiol.     Publication Date:  1992 Nov 
Date Detail:
Created Date:  1993-02-04     Completed Date:  1993-02-04     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7910653     Medline TA:  Am J Epidemiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1241-7     Citation Subset:  IM    
Affiliation:
Department of Medicine, Veterans Affairs Medical Center, San Francisco, CA 94121.
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MeSH Terms
Descriptor/Qualifier:
Aged*
Aged, 80 and over
Blood Pressure / drug effects*
Calcium, Dietary / pharmacology*
Cross-Sectional Studies
Female
Fractures, Bone / etiology,  prevention & control
Humans
Linear Models
Multivariate Analysis
Osteoporosis, Postmenopausal / complications
Prospective Studies
Questionnaires
Grant Support
ID/Acronym/Agency:
AG05407/AG/NIA NIH HHS; AG5394/AG/NIA NIH HHS; AR35582-4/AR/NIAMS NIH HHS
Chemical
Reg. No./Substance:
0/Calcium, Dietary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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