| Calcium homeostasis and exercise. | |
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MedLine Citation:
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PMID: 2722319 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Calcium homeostasis is altered by strenuous physical exercise. The mechanism is unclear. Our study was designed to investigate this relationship, particularly any associated changes in the calcium regulating hormones. Six subjects carried out a strenuous exercise programme for 10 min on a bicycle ergometer. Blood samples were analysed for ionized calcium, total calcium, calcitonin and pH. Plasma parathormone was assayed using a new and very sensitive N-terminal assay. Serum ionized calcium was significantly elevated by exercise at 50% of maximum aerobic capacity (VO2 max). The rise persisted until the late recovery phase, when it fell significantly below resting levels. Plasma parathormone levels were initially depressed by moderate exercise (50% VO2 max.) but were significantly elevated during and immediately after severe exercise. Our results suggest that exercise stimulates the hormonal, osteolytic influences acting on the skeleton, with increases in plasma parathormone and mobilisation of calcium stores. These changes may provide a supply of raw material allowing the osteogenic mechanical forces initiated by exercise to produce a positive skeletal balance. In view of the possible relevance of these findings to the understanding and management of osteoporosis we feel that this area merits further study. |
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Authors:
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S A Henderson; H K Graham; R A Mollan; C Riddoch; B Sheridan; H Johnston |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International orthopaedics Volume: 13 ISSN: 0341-2695 ISO Abbreviation: Int Orthop Publication Date: 1989 |
Date Detail:
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Created Date: 1989-07-05 Completed Date: 1989-07-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7705431 Medline TA: Int Orthop Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 69-73 Citation Subset: IM |
Affiliation:
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Department of Orthopaedic Surgery, Queen's University of Belfast, Musgrave Park Hospital, Belfast, Northern Ireland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Calcitonin / blood Calcium / blood, metabolism* Exercise* Homeostasis* Humans Hydrogen-Ion Concentration Male Parathyroid Hormone / blood |
| Chemical | |
Reg. No./Substance:
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0/Parathyroid Hormone; 7440-70-2/Calcium; 9007-12-9/Calcitonin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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