| Calcium dobesilate-induced agranulocytosis. | |
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MedLine Citation:
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PMID: 9368927 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Here we report a case of a patient in whom the administration of calcium dobesilate was associated with the development of an agranulocytosis episode. Eight weeks after the beginning of the treatment he was hospitalized with fever and leucopenia. Bone marrow biopsy showed a maturative promyelocytic interruption. All medication was withdrawn and blood cell count was completely recovered 7 days after admission. G-CSF was administered. A detailed study was performed and causal relationship was not suggestive for the other three drugs the patient was receiving. To date, there have only been reported two cases of calcium dobesilate induced agranulocytosis. |
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Authors:
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E García Benayas; B García Díaz; G Pérez |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pharmacy world & science : PWS Volume: 19 ISSN: 0928-1231 ISO Abbreviation: Pharm World Sci Publication Date: 1997 Oct |
Date Detail:
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Created Date: 1998-01-29 Completed Date: 1998-01-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9307352 Medline TA: Pharm World Sci Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 251-2 Citation Subset: IM |
Affiliation:
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Severo Ochoa Hospital, Madrid, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Agranulocytosis
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chemically induced* Calcium Dobesilate / adverse effects* Diabetes Mellitus, Type 2 / complications Diabetic Retinopathy / drug therapy, etiology Hemostatics / adverse effects* Humans Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Hemostatics; 20123-80-2/Calcium Dobesilate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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