Document Detail


Calcium cytochemistry and stereological morphometry of the intercalated ductal cells of the pancreas.
MedLine Citation:
PMID:  2931589     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Using K-antimonate procedure, Ca2 binding sites in pancreatic small ductal cells were studied. Great precipitates were observed in the lumen of intercalated ducts, on luminal, contraluminal and lateral plasmalemma of centroacinar cells and in some of their organelles especially in mitochondrial matrix as well as on the euchromatin. Fine precipitates were present mainly on the endomembranes of perinuclear cisternae, endoplasmic reticulum, Golgi vesicles, mitochondria, secretory vesicles. Stereological studies showed in electron micrographs great differences from one cell type to another for the volume of mitochondria: 8% in acinar cell, 4.8% in centroacinar cell, 15.3% in small ductal cell and 4% in endocrine cell. The results strongly support the idea that centroacinar and intercalated ductal cells constitute the segments of pancreatic excretory cells, where the alkalinization of pancreatic juice takes place mainly by the secretion of bicarbonate and resorption of chloride ions.
Authors:
I Diculescu; D Onicescu; H Hussein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Morphologie et embryologie     Volume:  31     ISSN:  0377-5038     ISO Abbreviation:  Morphol Embryol (Bucur)     Publication Date:    1985 Jul-Sep
Date Detail:
Created Date:  1985-11-12     Completed Date:  1985-11-12     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7512183     Medline TA:  Morphol Embryol (Bucur)     Country:  ROMANIA    
Other Details:
Languages:  eng     Pagination:  169-72     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Antimony / diagnostic use
Calcium / metabolism*
Cell Compartmentation
Intracellular Membranes / metabolism
Microscopy, Electron
Mitochondria / metabolism
Pancreas / metabolism*,  ultrastructure
Rats
Chemical
Reg. No./Substance:
7440-36-0/Antimony; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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