Document Detail


Calcium content and concretions of pineal glands of young and old rats. A scanning and X-ray microanalytical study.
MedLine Citation:
PMID:  1878938     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Calcium content and pineal concretions were studied in young (2-3 months) and old (28 months) Wistar rats. Samples, deep-frozen by liquid propane isopentane and freeze-dried were analysed by means of X-ray microanalysis in a scanning electron microscope. Total semi-quantitative measurements revealed that pineals of old rats showed a marked increase of calcium compared with the pineals of young rats. It is thus suggested that a calcium-rich environment is responsible for the growth of pineal concretions, which only appear in old rats. Pineal calcifications in rats could thus be an indicator of aging and/or of a degenerating state.
Authors:
W Humbert; P Pévet
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell and tissue research     Volume:  263     ISSN:  0302-766X     ISO Abbreviation:  Cell Tissue Res.     Publication Date:  1991 Mar 
Date Detail:
Created Date:  1991-10-01     Completed Date:  1991-10-01     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0417625     Medline TA:  Cell Tissue Res     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  593-6     Citation Subset:  IM    
Affiliation:
CNRS-URA 1332 Neurobiologie des fonctions rythmiques et saisonnières, Laboratoire de Zoologie, Strasbourg, France.
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MeSH Terms
Descriptor/Qualifier:
Aging / metabolism*
Animals
Calcium / analysis*,  metabolism
Electron Probe Microanalysis
Male
Microscopy, Electron, Scanning
Pineal Gland / chemistry*,  metabolism,  ultrastructure
Rats
Rats, Inbred Strains
Chemical
Reg. No./Substance:
7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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