| Calcium-alkali syndrome-like symptoms manifested by daily alphacalcidol and thiazide. | |
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MedLine Citation:
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PMID: 20453404 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 73-year-old man was admitted with complaints of a 2-month history of generalized weakness and numbness. Laboratory examination revealed hypercalcemia, metabolic alkalosis, and kidney injury, similar to the traditional milk-alkali syndrome. The clinical history and the response to therapy indicated that alphacalcidol and thiazide taken daily were the cause. Recently, it has been recommended the term "milk-alkali syndrome" be replaced by "calcium-alkali syndrome", which broadens the definition of the condition. This case suggests that the calcium-alkali syndrome can occur without calcium and alkali, but rather with alphacalcidol and a thiazide diuretic. |
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Authors:
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Fumie Satoh; Tomokazu Okado; Mari Iwamoto; Wataru Akita; Mai Wakabayashi; Akihito Ohta; Eisei Sohara; Yumi Noda; Tatemitsu Rai; Shinichi Uchida; Sei Sasaki |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-04-30 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 49 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-05-10 Completed Date: 2010-08-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 837-40 Citation Subset: IM |
Affiliation:
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Department of Nephrology, Tokyo Medical and Dental University. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Blood Chemical Analysis Combined Modality Therapy Disease Progression Dose-Response Relationship, Drug Drug Administration Schedule Follow-Up Studies Humans Hydrochlorothiazide / administration & dosage, adverse effects* Hydroxycholecalciferols / administration & dosage, adverse effects* Hypercalcemia / chemically induced*, diagnosis Kidney Failure, Acute / etiology*, physiopathology, therapy Kidney Function Tests Male Risk Assessment Severity of Illness Index Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Hydroxycholecalciferols; 41294-56-8/1-hydroxycholecalciferol; 58-93-5/Hydrochlorothiazide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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