Document Detail

Calcium administration during cardiac arrest: a systematic review.
MedLine Citation:
PMID:  22990036     Owner:  NLM     Status:  MEDLINE    
This topic highlights the results of the literature review on calcium therapy during cardiac arrest and cardiopulmonary resuscitation according to the Patient/population, Intervention, Comparator, Outcome structure. Eligible studies were assigned to one of the five levels of evidence. Their quality was rated as either good, fair, or poor and then classified as supportive, neutral, or opposing according to the outcome benefits. Among the 48 articles retrieved, 10 articles fulfilled all the criteria for analysis for the Guidelines preparation. There is no evidence that the administration of calcium during cardiopulmonary resuscitation improves survival from cardiac arrest irrespective of the presenting rhythm. In the setting of hyperkalemia, calcium channel blocker intoxication, hypocalcemia, and hypermagnesemia, the role of calcium remains unclear because of the limited amount of evidence. The main limitation is the scarcity of data, most of which relate to anoxic cardiac arrest, accounting for no more than 25% of the causes of cardiac arrest in humans.
Fulvio Kette; Jaspinder Ghuman; Michael Parr
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European journal of emergency medicine : official journal of the European Society for Emergency Medicine     Volume:  20     ISSN:  1473-5695     ISO Abbreviation:  Eur J Emerg Med     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-02-25     Completed Date:  2013-08-22     Revised Date:  2014-09-08    
Medline Journal Info:
Nlm Unique ID:  9442482     Medline TA:  Eur J Emerg Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  72-8     Citation Subset:  IM    
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MeSH Terms
Calcium Compounds / administration & dosage*
Cardiopulmonary Resuscitation / methods*
Heart Arrest / diagnosis,  mortality*,  therapy*
Practice Guidelines as Topic
Reference Values
Risk Assessment
Survival Rate
Treatment Outcome
Reg. No./Substance:
0/Calcium Compounds
Comment In:
Ann Emerg Med. 2014 Aug;64(2):187-9   [PMID:  23992943 ]

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