| Calcium absorption in rats with distal intestinal resection: influence of type of dietary fat, cholecalciferol and nature of the adaptative response. | |
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MedLine Citation:
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PMID: 8698548 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of dietary fat and supplementation with cholecalciferol on calcium absorption at different luminal concentrations (2.07 mmol/l and 2.07 mmol/l with 0.5 mmol/l 2,4-dinitrophenol and 8.20 mmol/l) were studied in vivo in the perfused duodenum, residual jejunum and proximal colon of rats with resection of 50% of the distal small intestine, as well as the nature of the adaptative response (passive or active). Changing the source of dietary fat (diet B, containing 1/3 medium chain triglycerides, 1/3 olive oil, 1/3 sunflower oil) increased calcium absorption, preferentially via active transport, in both transected and resected rats. Supplementation of diet B with cholecalciferol further enhanced intestinal calcium absorption, especially in the colon. These results suggest the importance of diet in the adaptive processes and confirm that active mechanisms of transport adapt more readily to intestinal resection than do passive mechanisms. |
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Authors:
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M J Alférez; I López-Aliaga; M Barrionuevo; F Lisbona; S Hartiti; I Pallarés; M S Campos |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition Volume: 66 ISSN: 0300-9831 ISO Abbreviation: Int J Vitam Nutr Res Publication Date: 1996 |
Date Detail:
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Created Date: 1996-08-30 Completed Date: 1996-08-30 Revised Date: 2007-02-21 |
Medline Journal Info:
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Nlm Unique ID: 1273304 Medline TA: Int J Vitam Nutr Res Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 59-65 Citation Subset: IM |
Affiliation:
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Department of Physiology, School of Pharmacy, University of Granada, Spain. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Physiological* Animals Calcium / metabolism* Cholecalciferol / pharmacology* Colon / metabolism Dietary Fats / pharmacology* Duodenum / metabolism Intestinal Absorption* Intestine, Small / physiology, surgery* Jejunum / metabolism Male Rats Rats, Wistar |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats; 67-97-0/Cholecalciferol; 7440-70-2/Calcium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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