Document Detail

Calciphylaxis in a patient with acute kidney injury and alcoholic cirrhosis.
MedLine Citation:
PMID:  22105455     Owner:  NLM     Status:  In-Data-Review    
Calciphylaxis is a rare disorder characterized by painful skin necrosis and calcification of small vessels which is seen mainly in the dialysis population. We describe a case of a patient with alcoholic cirrhosis developing calciphylaxis during an episode of acute kidney injury. We also review the literature in prior cases and postulate that unrecognized renal dysfunction in cirrhotic patients may have played a role in the development of this uncommon disorder. Our patient had complete recovery of the lesions with conservative treatment which coincided with recovery of her renal function. This case serves to highlight how small changes in creatinine levels in patients with cirrhosis may represent larger and clinically relevant changes in actual renal function that predispose these patients to calciphylaxis.
P Wichienkuer; W Naugler; R Wusirika
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nephrology     Volume:  76     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  499-503     Citation Subset:  IM    
Department of Medicine, Division of Gastroenterology, and Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, OR, USA.
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