Document Detail

Calciphylaxis: a devastating complication of derangements of calcium-phosphorus metabolism--a case report and review of the literature.
MedLine Citation:
PMID:  24308109     Owner:  NLM     Status:  In-Process    
Calciphylaxis is a rare and potentially devastating condition also referred to as uremic gangrene syndrome, calcific uremic arteriolopathy, metastatic calcification, and uremic small-vessel disease that can present in patients with end stage renal disease. This article reports a case of a 38-year-old African-American female on peritoneal dialysis for six years with a known history of non-adherence with diet, medications, and prescribed peritoneal dialysis treatment regimen. At her monthly clinic visit, the patient complained of burning sensation in the fingers of both hands with limited fine motor movement due to edema and severe pain. A presumptive diagnosis of calciphylaxis led to hospital admission with confirmation by X-ray of her hands. The patient was switched to hemodialysis with low calcium dialysate, aggressive reduction in phosphorus, diet counseling, use of cinacalcet, and six weeks of intravenous sodium thiosulfate infusion with hemodialysis treatments. The patient's condition improved with resolution of symptoms. This case was chosen based on the rarity of a calciphylaxis presentation and paucity of knowledge regarding diagnosis and treatment.
Trish Carter; Shobha Ratnam
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nephrology nursing journal : journal of the American Nephrology Nurses' Association     Volume:  40     ISSN:  1526-744X     ISO Abbreviation:  Nephrol Nurs J     Publication Date:    2013 Sep-Oct
Date Detail:
Created Date:  2013-12-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100909377     Medline TA:  Nephrol Nurs J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  431-5; quiz 436     Citation Subset:  N    
Department of Medicine, Division of Nephrology, University of Toledo Medical Center, Toledo, OH, USA.
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