Document Detail

Calcinosis cutis complicated by compartment syndrome following extravasation of calcium gluconate in a neonate: a case report.
MedLine Citation:
PMID:  20713289     Owner:  NLM     Status:  MEDLINE    
Hypocalcemia most frequently occurs in premature neonates. It is usually treated by intravenous (iv) calcium supplementation. However, complications caused by extravasation of iv calcium gluconate include localized soft tissue calcification, necrosis, cellulitis, osteomyelitis, and even compartment syndrome. We present a rare case of iatrogenic calcinosis cutis complicated by compartment syndrome secondary to extravasation of iv calcium gluconate in a neonate. Emergent fasciotomy was performed twice for decompression of compartment syndrome. Histologic findings revealed necrosis and calcification. Appropriate antibiotics were administered to control secondary infection. To the best of our knowledge, there were no previous case reports of calcinosis cutis with compartment syndrome in infants. Although iatrogenic calcinosis cutis is generally a benign entity, the early recognition of the presentation of extravasation of calcium gluconate is important to avoid severe complications and possible medical malpractice disputes. This report aims to raise doctors' awareness of the presentation, course, and management of this relatively rare iatrogenic complication.
Tuo-Kang Chen; Chueh-Yuan Yang; Shu-Jen Chen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatrics and neonatology     Volume:  51     ISSN:  1875-9572     ISO Abbreviation:  Pediatr Neonatol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-17     Completed Date:  2010-12-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101484755     Medline TA:  Pediatr Neonatol     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  238-41     Citation Subset:  IM    
Department of Pediatrics, Keelung Hospital, Keelung, Taiwan.
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MeSH Terms
Calcinosis / chemically induced*,  diagnosis,  therapy
Calcium Gluconate / adverse effects*
Compartment Syndromes / diagnosis,  etiology*,  therapy
Extravasation of Diagnostic and Therapeutic Materials / complications*
Hypocalcemia / complications,  drug therapy*,  pathology
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases
Skin Diseases / chemically induced*,  diagnosis,  therapy
Reg. No./Substance:
299-28-5/Calcium Gluconate

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