Document Detail

Calcifications in pituitary adenomas.
MedLine Citation:
PMID:  6264639     Owner:  NLM     Status:  MEDLINE    
In a surgical series of 755 pituitary adenomas, 51 cases (6.75%) showed intratumoral calcifications on microscopic examination and 13 of these were visible on roentgenographic examination (1.72%). Thirty-eight of these 51 cases were prolactinomas, the highest incidence being in male patients. There was no correlation between age, sex, levels of hormone, size of the tumor, and the presence of calcifications. Four patterns of radiological calcifications were encountered. Histologically, the calcifications were most frequently found within the tumor masses. Their rare occurrence within fibrous or degenerative areas speaks against their dystrophic nature. Previously reported calcified bodies in fetal and newborn pituitaries and the recently described physiological hyperprolactinemia in early infancy suggest a possible hormonal influence in the genesis of calcifications in prolactinomas.
B Rilliet; G Mohr; F Robert; J Hardy
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Surgical neurology     Volume:  15     ISSN:  0090-3019     ISO Abbreviation:  Surg Neurol     Publication Date:  1981 Apr 
Date Detail:
Created Date:  1981-08-10     Completed Date:  1981-08-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0367070     Medline TA:  Surg Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  249-55     Citation Subset:  IM    
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MeSH Terms
Adenoma / complications*,  secretion
Adrenocorticotropic Hormone / secretion
Calcinosis / complications*
Growth Hormone / secretion
Pituitary Neoplasms / complications*,  secretion
Prolactin / secretion
Thyrotropin / secretion
beta-Lipotropin / secretion
Reg. No./Substance:
9002-60-2/Adrenocorticotropic Hormone; 9002-62-4/Prolactin; 9002-71-5/Thyrotropin; 9002-72-6/Growth Hormone; 9035-55-6/beta-Lipotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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