| Caged glucosamine-6-phosphate for the light-control of riboswitch activity. | |
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MedLine Citation:
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PMID: 22005771 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We have synthesized a light-activatable ("caged") derivative of glucosamine-6-phosphate (GlcN6P), which only upon irradiation becomes a cofactor for the glmS riboswitch. This glmS riboswitch maintains its activity when embedded in the 3'-untranslated region of eukaryotic mRNA molecules and caged GlcN6P reduces the amount of translated EGFP upon irradiation with light in vitro. |
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Authors:
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Bernhard Wulffen; Maximilian Clemens Rudolf Buff; Monika Pofahl; Günter Mayer; Alexander Heckel |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-17 |
Journal Detail:
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Title: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology Volume: - ISSN: 1474-9092 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101124451 Medline TA: Photochem Photobiol Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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University of Bonn, Life and Medical Sciences, c/o Kekulé-Institute for Organic Chemistry and Biochemistry, Gerhard-Domagk-Str. 1, 53121, Bonn, Germany. gmayer@uni-bonn.de. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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