Document Detail

Caffeine's Mechanisms of Action and Its Cosmetic Use.
MedLine Citation:
PMID:  23075568     Owner:  NLM     Status:  Publisher    
Caffeine is being increasingly used in cosmetics due to its high biological activity and ability to penetrate the skin barrier. This alkaloid is frequently used as a hydrophilic model substance in human and animal skin penetration as well as different synthetic membrane using Franz diffusion cell experiments. The commercially available topical formulations of caffeine normally contain 3% caffeine. As for a cosmetic purpose, caffeine is used as an active compound in anti-cellulite products because it prevents excessive accumulation of fat in cells. This alkaloid stimulates the degradation of fats during lipolysis through inhibition of the phosphodiesterase activity. Caffeine has potent antioxidant properties. It helps protect cells against the UV radiation and slows down the process of photoaging of the skin. Moreover, caffeine contained in cosmetics increases the microcirculation of blood in the skin and also stimulates the growth of hair through inhibition of the 5-α-reductase activity.
A Herman; A P Herman
Related Documents :
2986398 - On the self-affinity of heparan sulfates from quiescent or proliferating normal 3t3 cel...
10585288 - Alphab-crystallin interacts with cytoplasmic intermediate filament bundles during mitosis.
1148328 - The in vitro cellular synthesis of hemoglobin components in various media and its relev...
3547078 - Antisense rna of proto-oncogene c-fos blocks renewed growth of quiescent 3t3 cells.
16491328 - Electrical and thermal characterization of nanochannels between a cell and a silicon ba...
3075618 - Tubulin post-translational modifications and the construction of microtubular organelle...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-11
Journal Detail:
Title:  Skin pharmacology and physiology     Volume:  26     ISSN:  1660-5535     ISO Abbreviation:  Skin Pharmacol Physiol     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101188418     Medline TA:  Skin Pharmacol Physiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  8-14     Citation Subset:  -    
Copyright Information:
Copyright © 2012 S. Karger AG, Basel.
Academy of Cosmetics and Health Care, Warsaw, Poland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Regulation of Contractile Proteins and Protein Translational Signaling in Disused Muscle.
Next Document:  Trends in population mental health before and after the 2008 recession: a repeat cross-sectional ana...