Document Detail


Caffeine, fatigue, and cognition.
MedLine Citation:
PMID:  14572506     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Effects of caffeine and fatigue are discussed with special attention to adenosine-dopamine interactions. Effects of caffeine on human cognition are diverse. Behavioural measurements indicate a general improvement in the efficiency of information processing after caffeine, while the EEG data support the general belief that caffeine acts as a stimulant. Studies using ERP measures indicate that caffeine has an effect on attention, which is independent of specific stimulus characteristics. Behavioural effects on response related processes turned out to be mainly related to more peripheral motor processes. Recent insights in adenosine and dopamine physiology and functionality and their relationships with fatigue point to a possible modulation by caffeine of mechanisms involved in the regulation of behavioural energy expenditure.
Authors:
Monicque M Lorist; Mattie Tops
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Brain and cognition     Volume:  53     ISSN:  0278-2626     ISO Abbreviation:  Brain Cogn     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-10-23     Completed Date:  2004-01-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8218014     Medline TA:  Brain Cogn     Country:  United States    
Other Details:
Languages:  eng     Pagination:  82-94     Citation Subset:  IM    
Affiliation:
Experimental and Work Psychology, University of Groningen, Groningen, The Netherlands. m.m.lorist@ppsw.rug.nl
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MeSH Terms
Descriptor/Qualifier:
Adenosine / metabolism
Attention / drug effects
Caffeine / pharmacology*
Central Nervous System Stimulants / pharmacology*
Cognition / drug effects*
Dopamine / metabolism
Electroencephalography
Fatigue / metabolism*
Humans
Reaction Time / drug effects
Chemical
Reg. No./Substance:
0/Central Nervous System Stimulants; 58-08-2/Caffeine; 58-61-7/Adenosine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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