Document Detail

Cafeteria behavior in the rat after hypothalamic cholinergic and adrenergic stimulation.
MedLine Citation:
PMID:  1187734     Owner:  NLM     Status:  MEDLINE    
Norepinephrine, carbachol, or placebo was micro-injected into the perifornical region of the rat hypothalamus, via stereotaxically implanted cannulas. Ingestive behavior was observed in the hour after injection in a cafeteria situation in which water, milk, mash, powdered food, and lab chow were all freely available. After adrenergic stimulation, animals ingested significant amounts of mash only; after cholinergic stimulation, animals ingested significant amounts of water and milk, but water was significantly preferred to milk. These findings are seen as providing further support for the behavioral specificity of direct chemical stimulation of the brain, and as casting serious doubts on the interpretation of milk-ingestion as eating behavior.
R B Montgomery; S Armstrong
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pharmacology, biochemistry, and behavior     Volume:  3     ISSN:  0091-3057     ISO Abbreviation:  Pharmacol. Biochem. Behav.     Publication Date:    1975 Jul-Aug
Date Detail:
Created Date:  1976-01-16     Completed Date:  1976-01-16     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0367050     Medline TA:  Pharmacol Biochem Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  709-11     Citation Subset:  IM    
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MeSH Terms
Carbachol / administration & dosage,  pharmacology
Feeding Behavior / drug effects*
Hypothalamus / physiology*
Norepinephrine / administration & dosage,  pharmacology
Parasympathetic Nervous System / physiology*
Stimulation, Chemical
Sympathetic Nervous System / physiology*
Reg. No./Substance:
51-41-2/Norepinephrine; 51-83-2/Carbachol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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