Document Detail


Caesarean section and gastrointestinal symptoms, atopic dermatitis, and sensitisation during the first year of life.
MedLine Citation:
PMID:  15499049     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: To investigate the effect of caesarean section on gastrointestinal symptoms, atopic dermatitis, and sensitisation to nutritional allergens in infants. METHODS: A total of 865 healthy full term neonates with parental history of allergy participating in the prospective German Infant Nutritional Intervention Program (GINI) were exclusively breast fed during the first four months of life and had a one year follow up. Data were obtained by follow up visits at age 1, 4, 8, and 12 months, weekly diaries for the first six months, and measurement of total and specific IgE at birth and 12 months. RESULTS: Infants born by caesarean section (147/865, 17%) had a greater risk of diarrhoea (OR(adj) 1.46, 95% CI 1.022 to 2.10) and sensitisation to food allergens, both in adjusted (OR(adj) 2.06, 95% CI 1.123 to 3.80) and stratified analyses (by cord blood IgE). Caesarean delivery was not associated with colicky pain and atopic dermatitis. CONCLUSION: Caesarean delivery might be a risk factor for diarrhoea and sensitisation in infants with family history of allergy. Further research in this area seems warranted as choosing caesarean section becomes increasingly popular.
Authors:
B Laubereau; B Filipiak-Pittroff; A von Berg; A Grübl; D Reinhardt; H E Wichmann; S Koletzko;
Related Documents :
724169 - Shoulder dystocia. a complication of fetal macrosomia and prolonged second stage of lab...
23774309 - Video/eeg findings in a kcnq2 epileptic encephalopathy: a case report and revision of l...
12521879 - Effect of postpartum anxiety on the colostral milk beta-endorphin concentrations of bre...
19773099 - Birth after caesarean section: changes over a nine-year period in one australian state.
366779 - Anaesthesia for caesarean section. an updated review of its special problems and their ...
24689979 - An integrative review of factors that influence breastfeeding duration for premature in...
14704319 - Modeling postnatal exposures and their interactions with birth size.
12177829 - Ontogeny of the pulmonary surfactant and antioxidant enzyme systems in the viviparous l...
25245229 - Use of lactoferrin in the newborn: where do we stand?
Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  89     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-10-22     Completed Date:  2004-11-16     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  England    
Other Details:
Languages:  eng     Pagination:  993-7     Citation Subset:  AIM; IM    
Affiliation:
GSF-National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Allergens / immunology
Breast Feeding
Cesarean Section / adverse effects*
Dermatitis, Atopic / etiology*
Diarrhea / etiology*
Female
Follow-Up Studies
Food Hypersensitivity / etiology*
Humans
Hypersensitivity / genetics
Immunoglobulin E / blood
Infant, Newborn
Male
Prospective Studies
Risk Factors
Chemical
Reg. No./Substance:
0/Allergens; 37341-29-0/Immunoglobulin E
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Long term cognitive development in children with prolonged crying.
Next Document:  Survey of administration of medicines to pupils in primary schools within the London area.