Document Detail


Caesarean before labour between 34 and 37 weeks: what are the risk factors of severe neonatal respiratory distress?
MedLine Citation:
PMID:  16243426     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess the frequency of severe neonatal respiratory distress and identify its risk factors in caesarean deliveries before labour between 34 and 37 weeks' gestation. STUDY DESIGN: Retrospective study of children born by caesarean delivery before labour between 34 and 37 weeks, between 1999 and 2003 in a level 3 maternity unit. The frequencies of severe and mild neonatal respiratory distress were calculated. Univariate and multivariate analyses studied the factors potentially associated with severe respiratory distress: gestational age, type of pregnancy (singleton or multiple), condition of membranes, maternal diabetes, indication for caesarean, antenatal corticosteroid therapy, intrauterine growth retardation, infant's sex and birth weight. RESULTS: The 189 study subjects included 107 singletons and 82 twins: 28% required intensive care for severe respiratory distress and 30.2% developed mild respiratory distress. Gestational age was a significant risk factor (p = 0.01), especially before 36 weeks (adjusted OR = 2.1; 95% CI: 1.0-4.4). The multivariate analysis indicated that singleton pregnancies (adjusted OR = 3.2; 95% CI: 1.5-6.7) and caesareans for fetal indications (adjusted OR = 2.7; 95% CI: 1.2-5.7) are also risk factors and that premature rupture of the membranes is a "protective" factor against respiratory complications (adjusted OR = 0.2; 95% CI: 0.1-0.8). CONCLUSION: More than a quarter of the infants delivered by caesarean before labour between 34 and 37 weeks' gestation in our level 3 maternity unit had severe respiratory distress. Although our population may not be typical of the general population, this finding and the risk factors associated with it should be taken into account in determining the best time and place for delivery of each patient.
Authors:
Camille Le Ray; Claire Boithias; Vanina Castaigne-Meary; Laurence Foix l'Hélias; Michèle Vial; René Frydman
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Publication Detail:
Type:  Journal Article     Date:  2005-10-21
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  127     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-03     Completed Date:  2008-01-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  56-60     Citation Subset:  IM    
Affiliation:
Department of Obstetrics-Gynecology and Neonatology, Service de Gynécologie-Obstétrique et Pédiatrie, Maternity of Antoine Béclère Hospital (APHP), 157, Rue de la Porte de Trivaux, 92141 Clamart, Cedex, France.
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Birth Weight
Cesarean Section / adverse effects*
Chi-Square Distribution
Female
Gestational Age
Humans
Incidence
Infant, Newborn
Infant, Premature
Male
Odds Ratio
Parity
Pregnancy
Respiratory Distress Syndrome, Newborn / epidemiology*,  etiology*
Resuscitation
Retrospective Studies
Risk Factors
Severity of Illness Index

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