Document Detail


Caerulein antagonism by benzodiazepines in the food intake in mice.
MedLine Citation:
PMID:  2866264     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intracisternal administration of caerulein inhibited the food intake in mice, but the caerulein action was antagonized by benzodiazepines such as chlordiazepoxide, diazepam and flurazepam which were administered intraperitoneally in low doses (0.2 to 2 mg/kg). The antagonism mechanism between caerulein and benzodiazepines remains unclear, but the characteristics of the antagonism were similar to those which had been observed with cholecystokinin and benzodiazepines.
Authors:
K Kubota; K Sugaya; I Matsuda; Y Matsuoka; M Itonaga
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese journal of pharmacology     Volume:  39     ISSN:  0021-5198     ISO Abbreviation:  Jpn. J. Pharmacol.     Publication Date:  1985 Sep 
Date Detail:
Created Date:  1986-01-15     Completed Date:  1986-01-15     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  2983305R     Medline TA:  Jpn J Pharmacol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  120-2     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Anxiety Agents / pharmacology*
Benzodiazepines
Caerulein / antagonists & inhibitors*
Depression, Chemical
Eating / drug effects*
Male
Mice
Sincalide / pharmacology
Time Factors
Chemical
Reg. No./Substance:
0/Anti-Anxiety Agents; 12794-10-4/Benzodiazepines; 17650-98-5/Caerulein; 25126-32-3/Sincalide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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