| Cadmium and zinc relationships in the liver and kidney of humans exposed to environmental cadmium. | |
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MedLine Citation:
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PMID: 7569880 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Concentrations of cadmium and zinc were determined in the liver and in the kidney (cortex and medulla) of subjects from the general population of Barcelona (Spain) by atomic absorption spectrometry. Tissues were collected from necropsies of 50 selected subjects without any occupational exposure to heavy metals. Cadmium levels calculated on a fresh tissue basis were 14.6 +/- 5.9 micrograms/g (2.4-31) in the kidney cortex, 8.6 +/- 4.3 micrograms/g (1.5-16.7) in the kidney medulla and 0.98 +/- 0.50 micrograms/g (0.32-2.32) in the liver. Zinc concentrations ranged between 18-53 micrograms/g, (mean +/- S.D.: 38.0 +/- 10 micrograms/g) in the kidney cortex, 25.0 +/- 7.7 micrograms/g (12-42 micrograms/g) in the kidney medulla and 41.7 +/- 18.3 micrograms/g (20-84 micrograms/g) in the liver. The aim of the present work was to study the association of cadmium and zinc in the kidney and in the liver of a human population with cadmium accumulation from an environmental origin. The results obtained showed a significant correlation between cadmium and zinc concentration in the liver (r = 0.86, P < 0.001), but not in the kidney. |
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Authors:
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M Torra; J To-Figueras; M Rodamilans; M Brunet; J Corbella |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Science of the total environment Volume: 170 ISSN: 0048-9697 ISO Abbreviation: Sci. Total Environ. Publication Date: 1995 Aug |
Date Detail:
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Created Date: 1995-10-24 Completed Date: 1995-10-24 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0330500 Medline TA: Sci Total Environ Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 53-7 Citation Subset: IM |
Affiliation:
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Toxicology Unit, Hospital Clínic i Provincial, Facultat de Medicina, Universitat de Barcelona, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Cadmium / analysis*, pharmacokinetics Environmental Exposure* Humans Kidney / chemistry* Liver / chemistry* Middle Aged Statistics as Topic Zinc / analysis* |
| Chemical | |
Reg. No./Substance:
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7440-43-9/Cadmium; 7440-66-6/Zinc |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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