Document Detail


Cadmium concentration in blood in an elderly urban population.
MedLine Citation:
PMID:  11247037     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Concentration of cadmium in blood in an elderly population with a mean age of 87 years was studied in relation to age, blood pressure, BMI, cognitive function, gender and smoking. This population-based study consisted of 804 subjects both men and women. Clinical examination included medical and social history, physical and neurologic examination, and assessment of cognitive functions with Mini-Mental State Examination (MMSE). Information on prescription and non-prescription drug use was collected. Anti-hypertensive drugs included all medicines potentially used for treating high blood pressure. Blood pressure was measured. Whole blood from 763 subjects was analysed for cadmium by atomic absorption spectrophotometry (GFAAS) with Zeeman background correction and with a graphite furnace using the L'vov platform technique including quality control. Differences in cadmium concentrations were related to non-smokers (3.9 nmol/l), previous smokers (4.4 nmol/l) and current smokers (7.5 nmol/l). There were no relations between cadmium and age, blood pressure or cognitive functions. In conclusion, increased cadmium levels were found in smokers. A possible contribution from previous occupational exposure needs to be further evaluated.
Authors:
M Nordberg; B Winblad; H Basun
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine     Volume:  13     ISSN:  0966-0844     ISO Abbreviation:  Biometals     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-03-14     Completed Date:  2001-04-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9208478     Medline TA:  Biometals     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  311-7     Citation Subset:  IM    
Affiliation:
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. monica.nordberg@imm.ki.se
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Blood Pressure
Body Mass Index
Cadmium / blood*
Cognition
Female
Humans
Male
Smoking / blood
Sweden
Urban Population
Chemical
Reg. No./Substance:
7440-43-9/Cadmium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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