| Cade's Identification of Lithium for Manic-Depressive Illness-The Prospector Who Found a Gold Nugget. | |
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MedLine Citation:
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PMID: 23197126 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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ABSTRACT: John Cade's identification of lithium as a treatment of manic-depressive illness has been judged as a landmark biomedical advance and as an initiator of modern psychopharmacology. His personal background, interests, character, experiences, and key observational skills are sketched to provide the background and logic for his discovery and to argue against his simple self-description as a clinician administrator. The Cade story illustrates the potential strengths of clinical research whereby the clinician observes "signals," formulates hypotheses and explanations, and then pursues or encourages their validity and application. The suggestion that Cade simply "rediscovered lithium" is rejected. |
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Authors:
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Neil Cole; Gordon Parker |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of nervous and mental disease Volume: 200 ISSN: 1539-736X ISO Abbreviation: J. Nerv. Ment. Dis. Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-11-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375402 Medline TA: J Nerv Ment Dis Country: United States |
Other Details:
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Languages: eng Pagination: 1101-4 Citation Subset: AIM; IM |
Affiliation:
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*Mental Health Research Institute, University of Melbourne, Melbourne, Australia; and †School of Psychiatry, University of New South Wales, Sydney, Australia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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