Document Detail


Cade's Identification of Lithium for Manic-Depressive Illness-The Prospector Who Found a Gold Nugget.
MedLine Citation:
PMID:  23197126     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
ABSTRACT: John Cade's identification of lithium as a treatment of manic-depressive illness has been judged as a landmark biomedical advance and as an initiator of modern psychopharmacology. His personal background, interests, character, experiences, and key observational skills are sketched to provide the background and logic for his discovery and to argue against his simple self-description as a clinician administrator. The Cade story illustrates the potential strengths of clinical research whereby the clinician observes "signals," formulates hypotheses and explanations, and then pursues or encourages their validity and application. The suggestion that Cade simply "rediscovered lithium" is rejected.
Authors:
Neil Cole; Gordon Parker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of nervous and mental disease     Volume:  200     ISSN:  1539-736X     ISO Abbreviation:  J. Nerv. Ment. Dis.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375402     Medline TA:  J Nerv Ment Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1101-4     Citation Subset:  AIM; IM    
Affiliation:
*Mental Health Research Institute, University of Melbourne, Melbourne, Australia; and †School of Psychiatry, University of New South Wales, Sydney, Australia.
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