Document Detail

Ca2+-induced excess capacitance fluctuation studied by phase-sensitive detection method in exocrine pancreatic acinar cells.
MedLine Citation:
PMID:  2431386     Owner:  NLM     Status:  MEDLINE    
A phase-sensitive detection method in combination with whole-cell voltage-clamp was applied to exocrine pancreatic acinar cells from rat. The results have shown that cell-aialysis with a solution containing 5 X 10(-7) M Ca2+ induces stp-wise changes in cell capacitance. The size distribution of increasing and decreasing capacitance steps is compatible with the idea that these capacitance steps are the results of individual granular fusion and retrieval events. This method may enable experiments studying the exo- and endo-cytotic mechanisms in morphologically polarized secretory cells.
Y Maruyama
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pflügers Archiv : European journal of physiology     Volume:  407     ISSN:  0031-6768     ISO Abbreviation:  Pflugers Arch.     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1987-01-12     Completed Date:  1987-01-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0154720     Medline TA:  Pflugers Arch     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  561-3     Citation Subset:  IM    
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MeSH Terms
Calcium / metabolism,  physiology*
Cell Membrane / metabolism
Cytological Techniques
Cytosol / metabolism
Ion Channels
Pancreas / cytology,  enzymology,  metabolism*
Reg. No./Substance:
0/Ion Channels; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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