Document Detail


Ca2+ channels: diversity of form and function.
MedLine Citation:
PMID:  1322749     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The past year has seen some significant advances in our understanding of the structural and functional properties of neuronal voltage-gated Ca2+ channels. Molecular cloning and protein purification studies have identified structural components, and expression studies are beginning to define the biophysical and pharmacological properties of the cloned channels. A number of studies of native Ca2+ channels show that the concept of channel modulation includes gating by both voltage and ligands.
Authors:
T P Snutch; P B Reiner
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current opinion in neurobiology     Volume:  2     ISSN:  0959-4388     ISO Abbreviation:  Curr. Opin. Neurobiol.     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1992-09-10     Completed Date:  1992-09-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9111376     Medline TA:  Curr Opin Neurobiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  247-53     Citation Subset:  IM    
Affiliation:
Biotechnology Laboratory, University of British Columbia, Vancouver, Canada.
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MeSH Terms
Descriptor/Qualifier:
Animals
Calcium Channels / physiology*
Humans
Ion Channel Gating
Neurons / metabolism,  physiology
Chemical
Reg. No./Substance:
0/Calcium Channels

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