Document Detail

CT volumetry of intravertebral cement after kyphoplasty. Comparison of polymethylmethacrylate and calcium phosphate in a 12-month follow-up.
MedLine Citation:
PMID:  15809829     Owner:  NLM     Status:  MEDLINE    
This study was intended to measure the volume of intravertebral cement after balloon kyphoplasty with high resolution computed tomography (CT) and dedicated software. Volume changes of biocompatible calcium phosphate cement (CPC) were detected during a follow-up of 12 months. Measurements were compared with a control group of patients treated with polymethylmethacrylate (PMMA). Twenty-three vertebrae (14 CPC, 9 PMMA) of 12 patients were examined with CT using an identical imaging protocol. Dedicated software was used to quantify intravertebral cement volume in subvoxel resolution by analyzing each cement implant with a density-weighted algorithm. The mean volume reduction of CPC was 0.08 ml after 12 months, which corresponds to an absorption rate of 2 vol%. However, the difference did not reach significance level (P>0.05). The mean error estimate was 0.005 ml, indicating excellent precision of the method. CT volumetry appears a precise tool for measurement of intravertebral cement volume. CT volumetry offers the possibility of in vivo measurement of CPC resorption.
M Libicher; M Vetter; I Wolf; G Noeldge; C Kasperk; I Grafe; K Da Fonseca; J Hillmeier; P J Meeder; H P Meinzer; G W Kauffmann
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2005-04-05
Journal Detail:
Title:  European radiology     Volume:  15     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-07-21     Completed Date:  2006-08-16     Revised Date:  2013-04-05    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1544-9     Citation Subset:  IM    
Department of Diagnostic Radiology, University of Heidelberg, Heidelberg, Germany.
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MeSH Terms
Bone Cements*
Calcium Phosphates*
Follow-Up Studies
Fractures, Compression / radiography,  surgery*
Lumbar Vertebrae / injuries
Middle Aged
Polymethyl Methacrylate*
Prospective Studies
Spinal Fractures / radiography,  surgery*
Thoracic Vertebrae / injuries
Time Factors
Tomography, X-Ray Computed*
Reg. No./Substance:
0/Bone Cements; 0/Calcium Phosphates; 9011-14-7/Polymethyl Methacrylate; 97Z1WI3NDX/calcium phosphate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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