Document Detail


CT virtual bronchoscopy of the central airways in patients with Wegener's granulomatosis.
MedLine Citation:
PMID:  11796457     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To compare CT virtual bronchoscopy (VB) to CT alone and to conventional bronchoscopy for evaluation of central airway stenoses in patients with Wegener's granulomatosis. DESIGN: Prospective observer study, in which 18 thin-section helical CT scans of the trachea and bronchi of 11 patients with Wegener's granulomatosis were obtained. VB was performed using surface rendering and was evaluated by one bronchoscopist and one radiologist in a blinded fashion. Bronchoscopic correlation within an average of 1.8 days of CT was available. MEASUREMENTS AND RESULTS: VB displayed 188 of 198 bronchi (95%). Thirty-two of 40 stenoses (80%) were detected by VB by at least one of two physicians (double reading), and 22 of 40 stenoses (55%) were detected by a third physician reading only the CT. CONCLUSIONS: VB depicts bronchi to the segmental level and detects the majority of central airway stenoses in patients with Wegener's granulomatosis. A team approach is useful to attain optimal clinical benefit from VB for these patients.
Authors:
Ronald M Summers; Neil R Aggarwal; Michael C Sneller; Mark J Cowan; Bradford J Wood; Carol A Langford; James H Shelhamer
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Chest     Volume:  121     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2002-01-17     Completed Date:  2002-02-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  242-50     Citation Subset:  AIM; IM    
Affiliation:
Diagnostic Radiology Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892-1182, USA. rms@nih.gov
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MeSH Terms
Descriptor/Qualifier:
Adult
Airway Obstruction / radiography*
Bronchography
Bronchoscopy*
Female
Humans
Image Processing, Computer-Assisted*
Male
Middle Aged
Observer Variation
Prospective Studies
Sensitivity and Specificity
Tomography, X-Ray Computed*
Tracheal Stenosis / radiography
User-Computer Interface*
Wegener Granulomatosis / radiography*
Comments/Corrections
Comment In:
Chest. 2002 Oct;122(4):1496; author reply 1496   [PMID:  12377892 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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