Document Detail


CT stress myocardial perfusion imaging using Multidetector CT-A review.
MedLine Citation:
PMID:  22146494     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Computed tomography coronary angiography (CTA) accurately detects and excludes coronary artery disease (CAD); however, the physiological significance of coronary artery lesions may be uncertain. CT myocardial perfusion imaging (CTP) acquired during vasodilator stress provides a novel and emerging method for detection of myocardial ischemia. Multiple studies have established the feasibility of CTP and suggested its incremental value when used in combination with CTA in the identification of hemodynamically significant stenoses as compared with CTA alone. Despite these encouraging clinical data, CT perfusion assessment is in its infancy, as further research is required to validate and optimize this new technique. Combined CTA/CTP imaging has significant potential, as it offers the convenience of assessing both coronary anatomy and myocardial perfusion in one single examination at a radiation dose equivalent to contemporary nuclear medicine imaging. In this review, we provide an overview of the fundamentals of CT perfusion imaging, recent advances in scanner types and imaging techniques and protocols, and current literature on the accuracy of CTP, concluding with its future challenges and directions.
Authors:
Brian S Ko; James D Cameron; Tony Defrance; Sujith K Seneviratne
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Publication Detail:
Type:  Journal Article     Date:  2011-10-24
Journal Detail:
Title:  Journal of cardiovascular computed tomography     Volume:  5     ISSN:  1876-861X     ISO Abbreviation:  J Cardiovasc Comput Tomogr     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-12-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101308347     Medline TA:  J Cardiovasc Comput Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  345-56     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Society of Cardiovascular Computed Tomography. All rights reserved.
Affiliation:
Monash Cardiovascular Research Centre, Monash HEART, Department of Medicine, Monash Medical Centre (MMC), Southern Health and Monash University, Melbourne, 246 Clayton Road, Clayton, 3168 VIC, Australia.
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