| CT scan patterns of pulmonary alveolar proteinosis in children. | |
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MedLine Citation:
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PMID: 10201029 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: To study computed tomographic (CT) findings in children with pulmonary alveolar proteinosis (PAP) more extensively. OBJECTIVE: To describe the CT features at the time of diagnosis and after therapeutic broncho-alveolar lavage (BAL). MATERIALS AND METHODS: We retrospectively reviewed the CT scans of five children (aged 3 months to 4 years) examined because of incidental bronchitis (n = 1), disease in a sibling (n = 1) and relapsing fever, cough and dyspnoea (n = 3). Each patient had an initial CT scan. Two asymptomatic cases were not treated but were followed up by plain chest films. The other three had BAL and follow-up CT. RESULTS: Initial CT in all cases showed a diffuse reticulomicronodular pattern associated in three cases with posterior bilateral alveolar infiltrates. CT in the two asymptomatic patients remained unchanged or slightly improved without BAL. After BAL, a variable decrease of lung infiltrates was observed. CONCLUSIONS: Correlation between the extent of alveolar consolidation and severity of disease was found. Anatomical and pathological considerations allow us to consider that the classical reticulomicronodular pattern is not due to an interstitial infiltration but to alveoli filled with the abnormal material characteristic of PAP. |
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Authors:
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V Albafouille; N Sayegh; S De Coudenhove; P Scheinmann; J De Blic; T Mamou-Mani; A Hassine; F Jaubert; F Brunelle |
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Publication Detail:
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Type: Case Reports; Comparative Study; Journal Article |
Journal Detail:
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Title: Pediatric radiology Volume: 29 ISSN: 0301-0449 ISO Abbreviation: Pediatr Radiol Publication Date: 1999 Mar |
Date Detail:
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Created Date: 1999-05-25 Completed Date: 1999-05-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0365332 Medline TA: Pediatr Radiol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 147-52 Citation Subset: IM |
Affiliation:
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Department of Paediatric Radiology, Hôpital Necker-Enfants Malades, Paris, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy Bronchoalveolar Lavage Child Child, Preschool Diagnosis, Differential Female Follow-Up Studies Humans Infant Male Pulmonary Alveolar Proteinosis / pathology, radiography*, therapy Retrospective Studies Severity of Illness Index Tomography, X-Ray Computed* |
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