Document Detail

CT-guided lung biopsy: incidence of pneumothorax after instillation of NaCl into the biopsy track.
MedLine Citation:
PMID:  18270713     Owner:  NLM     Status:  MEDLINE    
This study was conducted to evaluate whether instillation of NaCl 0.9% solution into the biopsy track reduces the incidence of pneumothoraces after CT-guided lung biopsy. A total of 140 consecutive patients with pulmonary lesions were included in this prospective study. All patients were alternatingly assigned to one of two groups: group A in whom the puncture access was sealed by instillation of NaCl 0.9% solution during extraction of the guide needle (n = 70) or group B for whom no sealing was performed (n = 70). CT-guided biopsy was performed with a 18-G coaxial system. Localization of lesion (pleural, peripheral, central), lesion size, needle-pleural angle, rate of pneumothorax and alveolar hemorrhage were evaluated. In group A, the incidence of pneumothorax was lower compared to group B (8%, 6/70 patients vs. 34%, 24/70 patients; P < 0.001). All pneumothoraces occurred directly post punctionem after extraction of the guide needle. One patient in group A and eight patients in group B developed large pneumothoraces requiring chest tube placement (P = 0.01). The frequency of pneumothorax was independent of other variables. After CT-guided biopsy, instillation of NaCl 0.9% solution into the puncture access during extraction of the needle significantly reduces the incidence of pneumothorax.
Christian Billich; Rainer Muche; Gerhard Brenner; Stefan A Schmidt; Stefan Krüger; Hans-Jürgen Brambs; Sandra Pauls
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Publication Detail:
Type:  Journal Article     Date:  2008-02-13
Journal Detail:
Title:  European radiology     Volume:  18     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-05-08     Completed Date:  2008-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1146-52     Citation Subset:  IM    
Department of Diagnostic and Interventional Radiology, University of Ulm, Robert-Koch-Str. 8, 89081 Ulm, Germany.
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MeSH Terms
Aged, 80 and over
Biopsy / adverse effects*
Chi-Square Distribution
Contrast Media
Lung Neoplasms / pathology*
Middle Aged
Pneumothorax / epidemiology,  prevention & control*,  radiography
Prospective Studies
Radiography, Interventional*
Sodium Chloride / administration & dosage*
Statistics, Nonparametric
Tomography, X-Ray Computed*
Reg. No./Substance:
0/Contrast Media; 7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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