Document Detail

CT findings in neonatal hypothermia.
MedLine Citation:
PMID:  9634453     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Newborn infants are particularly prone to hypothermia, a condition with a high mortality. OBJECTIVE: To study the CT brain patterns in infants with hypothermia and neurological symptoms. MATERIALS AND METHODS: We reviewed the brain CT of nine infants with neonatal hypothermia, multiple organ failure, seizures and coma. RESULTS: Two infants had normal CT scans, acutely and at follow-up, and were clinically normal at follow-up. In seven infants, CT showed diffuse cerebral oedema, with reversal of the normal density relationship between grey and white matter and a relative increased density of the thalami, brainstem and cerebellum - the 'reversal sign'. In six surviving infants with severe developmental delay, follow-up CT revealed cerebral atrophy with multicystic encephalomalacia. CONCLUSIONS: The 'reversal sign' has been described in the abused child, birth asphyxia and anoxia due to drowning. Neonatal hypothermia is offered as a further cause.
H Schulman; L Laufer; J Berginer; E Hershkowitz; T Berenstein; S Sofer; E Maor; Y Hertzanu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric radiology     Volume:  28     ISSN:  0301-0449     ISO Abbreviation:  Pediatr Radiol     Publication Date:  1998 Jun 
Date Detail:
Created Date:  1998-08-14     Completed Date:  1998-08-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  414-7     Citation Subset:  IM    
Department of Radiology, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, P. O. Box 151, Beer-Sheva 84101, Israel.
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MeSH Terms
Brain / radiography*
Brain Damage, Chronic / etiology
Brain Edema / etiology,  radiography
Follow-Up Studies
Hypothermia / complications,  radiography*
Infant, Newborn
Time Factors
Tomography, X-Ray Computed*

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