| CT findings in autoimmune pancreatitis: assessment using multiphase contrast-enhanced multisection CT. | |
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MedLine Citation:
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PMID: 20696301 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To assess the spectrum of findings using multiphase contrast-enhanced computed tomography (CT) in patients with autoimmune pancreatitis (AIP). MATERIALS AND METHODS: Fifty patients (four female and 46 male, mean age 65 years) were retrospectively identified from consecutive patients with abnormal CT findings of the pancreas and negative work-up for known causes. These patients had at least one finding supporting the diagnosis of AIP: serological abnormality, histopathological abnormality, or response to steroid. Two radiologists evaluated multiphase contrast-enhanced CT images in consensus. RESULTS: The pancreas showed diffuse enlargement (n=16; 32%), focal enlargement (n=18; 36%), or no enlargement (n=16; 32%). Forty-nine (98%) patients showed abnormal contrast enhancement in the affected pancreatic parenchyma, including hypoattenuation during the pancreatic phase (n=45; 90%) and hyperattenuation during the delayed phase (n=39; 87%). The following findings were also seen in the pancreas: a capsule-like rim (n=24; 48%); no visualization of the main pancreatic duct lumen (n=48; 96%); ductal enhancement (n=26; 52%); upstream dilatation of the main pancreatic duct (n=27; 54%); upstream atrophy of the pancreatic parenchyma (n=27; 54%); calcification (n=7; 14%); and cysts (n=5; 10%). Forty-two (84%) patients showed one or more of the following extrapancreatic findings: biliary duct or gallbladder abnormality (n=40; 80%); peripancreatic (n=8; 16%) or para-aortic (n=10; 20%) soft-tissue proliferation; and renal involvement (n=15; 30%). CONCLUSION: Patients with AIP presented with a variety of CT findings in the pancreas and the extrapancreatic organs. The present study highlights pancreatic ductal enhancement in a subset of patients with AIP. |
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Authors:
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K Suzuki; S Itoh; T Nagasaka; H Ogawa; T Ota; S Naganawa |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical radiology Volume: 65 ISSN: 1365-229X ISO Abbreviation: Clin Radiol Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-10 Completed Date: 2010-11-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1306016 Medline TA: Clin Radiol Country: England |
Other Details:
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Languages: eng Pagination: 735-43 Citation Subset: IM |
Affiliation:
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Department of Radiology, Nagoya University Graduate School of Medicine, Shouwaku, Nagoya, Japan. Kojiro@med.nagoya-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Autoimmune Diseases / pathology, radiography* Contrast Media / diagnostic use* Diagnosis, Differential Female Humans Male Pancreatic Neoplasms / diagnosis, pathology Pancreatitis / pathology, radiography* Retrospective Studies Tomography, X-Ray Computed / methods* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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