Document Detail


CT, endoscopic sonography, and a combined protocol for preoperative evaluation of pancreatic insulinomas.
MedLine Citation:
PMID:  14500214     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: This study aimed to determine the value of CT, endoscopic sonography, and a combined protocol for preoperative detection of insulinomas. MATERIALS AND METHODS: All patients treated in our institution for surgically proven insulinoma between 1987 and 2000 were retrospectively reviewed. Thirty patients with 32 pancreatic insulinomas underwent preoperative CT and endoscopic sonography and were included in the study. These 30 patients also underwent dual-phase thin-section multidetector CT (group 1: n = 15), dual-phase multidetector CT without thin sections (group 2: n = 8), or sequential CT (group 3: n = 7). CT scans were interpreted separately and retrospectively by three radiologists in consensus. Sensitivity values for CT, endoscopic sonography, and a combined protocol were determined. RESULTS: The overall diagnostic sensitivity for dual-phase helical CT was 94.4% for group 1, 57.1% for group 2, and 28.6% for group 3. Endoscopic sonography showed proven insulinomas in 30 of 32 cases (sensitivity, 93.8%). Differences between dual-phase thin-section CT and endoscopic sonography were not statistically significant. The overall diagnostic sensitivity for combined biphasic thin-section helical CT and endoscopic sonography was 100%. CONCLUSION: The most effective method for revealing insulinomas is a combined imaging protocol that consists of both dual-phase thin-section multidetector CT and endoscopic sonography.
Authors:
Hervé Gouya; Olivier Vignaux; Joelle Augui; Bertrand Dousset; Laurent Palazzo; André Louvel; Stanislas Chaussade; Paul Legmann
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  181     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-09-22     Completed Date:  2003-11-17     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  987-92     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, Université René Descartes, Hôpital Cochin, 27 rue du Fg Saint Jacques, 75679 Paris Cedex 14, France.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Child
Clinical Protocols
Endoscopy, Digestive System
Female
Humans
Insulinoma / diagnosis,  radiography*,  ultrasonography*
Male
Middle Aged
Pancreas
Pancreatic Neoplasms / diagnosis,  radiography*,  ultrasonography*
Preoperative Care
Retrospective Studies
Tomography, X-Ray Computed*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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