Document Detail

CT detection of subendocardial fat in myocardial infarction.
MedLine Citation:
PMID:  19155421     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: We sought to systemically analyze the characteristics of fat accumulation in patients with myocardial infarction (MI) relative to various clinical parameters. MATERIALS AND METHODS: We included 161 patients (129 men, 32 women; mean age, 60.7 years) who had previously been diagnosed with MI and had undergone CT coronary angiography between February 2003 and April 2005. We analyzed the characteristics of myocardial fat, if present, and compared the clinical parameters of the patients with and those without myocardial fat. RESULTS: Myocardial fat was found in the subendocardial region in 36 (22.4%) patients with MI. In all cases, the myocardial fat was located in the subendocardial region and was typically detected in the left anterior descending artery territory (75%, n = 27). The mean attenuation value of myocardial fat was -29.6 HU on unenhanced CT. Myocardial fat was more frequently associated with a greater infarct age, milder coronary artery stenosis, and fewer number of diseased vessels. Patients with myocardial fat had more severe regional wall motion abnormalities on follow-up echocardiography. Age, sex, the presence of ST elevation or Q wave, elevated levels of cardiac enzymes, ejection fraction, and end-diastolic left ventricular dimension on follow-up echocardiography, as well as the presence of arrhythmia, were not significantly different between the two groups. CONCLUSION: Myocardial fat was detected in 22.4% of MI patients and was more frequently associated with a longer postinfarct period, milder coronary artery stenosis, fewer number of diseased vessels, and more severe regional wall motion abnormalities.
Sung Soo Ahn; Young-Jin Kim; Jin Hur; Hye-Jeong Lee; Tae Hoon Kim; Kyu Ok Choe; Byoung Wook Choi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  192     ISSN:  1546-3141     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-01-21     Completed Date:  2009-02-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  532-7     Citation Subset:  AIM; IM    
Department of Diagnostic Radiology, Severance Hospital, Seodaemun-gu, Seoul, South Korea.
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MeSH Terms
Adipose Tissue / radiography*
Contrast Media
Coronary Angiography / methods*
Iopamidol / diagnostic use
Logistic Models
Middle Aged
Myocardial Infarction / pathology*
Retrospective Studies
Tomography, X-Ray Computed / methods*
Reg. No./Substance:
0/Contrast Media; 62883-00-5/Iopamidol

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