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CT colonography and transient bacteraemia: implications for antibiotic prophylaxis.
MedLine Citation:
PMID:  20711729     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVES: To determine the prevalence of transient bacteraemia after CT colonography (CTC).
METHODS: Blood cultures were obtained at 5, 10 and 15 min after CTC from 100 consecutive consenting patients. Blood samples were cultured in both aerobic and anaerobic media and positive blood culture samples were analysed by a microbiologist.
RESULTS: Blood culture samples were positive for growth in sixteen patients. All positive blood culture samples were confirmed skin contaminants. There were no cases of significant bacteraemia. The estimated significant bacteraemia rate as a result of CTC is 0-3.7%, based on 95% confidence intervals around extreme results using Wilson's score method.
CONCLUSIONS: American Heart Association and National Institute for Clinical Excellence guidelines advise that antibiotic prophylaxis before lower gastrointestinal endoscopy is not indicated in patients with at risk cardiac lesions (ARCL) as the risk of a transient bacteraemia leading to infective endocarditis is low. These data show that the prevalence of transient bacteraemia after CTC is also low. It follows that patients with ARCL do not require antibiotic prophylaxis before CTC.
Authors:
C A Ridge; M R Carter; L P Browne; R Ryan; C Hegarty; K Schaffer; D E Malone
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Publication Detail:
Type:  Journal Article     Date:  2010-08-15
Journal Detail:
Title:  European radiology     Volume:  21     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  360-5     Citation Subset:  IM    
Affiliation:
Department of Radiology, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland, caroleridge@hotmail.com.
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