Document Detail

CT angiography of pulmonary embolism using a 64 slice multi-detector scanner.
MedLine Citation:
PMID:  20079168     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Multi-detector computed tomography (MDCT) has already been the first line investigation method for diagnosis of pulmonary embolism (PE). Reducing the amount of contrast medium used during CT scanning could decrease the incidental rate of adverse reactions. Our study amied to evaluate the image quality of pulmonary arteries using 64 slice multi-detector CT with small volumes of contrast media injection. METHODS: Forty nonconsecutive patients without PE or other lung diseases were randomly assigned to two groups. Group A underwent CT scanning with 16 x 1.25 mm collimation and a 70 ml contrast injection, while group B had CT with 64 x 0.625 mm collimation and 20 ml of contrast injection. Two readers independently depicted the segmental and subsegmental pulmonary arteries. Reasons we could not analyze the pulmonary artery or that led to misdiagnosis of pulmonary embolism were evaluated, including the degree of contrast enhancement of the main pulmonary artery, and factors that caused misdiagnosis of PE (flow-related artifacts, partial volume artifact, beam-hardening artifacts and enhancement of pulmonary vein). The independent samples t-test, Mann-Whitney U test and Pearson chi-square test were applied. RESULTS: There were no significant differences in image quality of segmental and subsegmental arteries between the two groups. No significant difference was found for factors that made pulmonary arteries non-analyzable or in the misdiagnosis of PE, except the degree of contrast enhancement. CONCLUSION: 64 x 0.625 mm collimation with 20 ml contrast injection could depict the pulmonary arteries well.
Nai-shan Qin; Xue-xiang Jiang; Jian-xing Qiu; Ying Zhu; Ji-chen Wang
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Chinese medical journal     Volume:  122     ISSN:  0366-6999     ISO Abbreviation:  Chin. Med. J.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2010-01-18     Completed Date:  2010-05-24     Revised Date:  2010-07-14    
Medline Journal Info:
Nlm Unique ID:  7513795     Medline TA:  Chin Med J (Engl)     Country:  China    
Other Details:
Languages:  eng     Pagination:  2509-15     Citation Subset:  IM    
Department of Radiology, Peking University First Hospital, No. 8, Xishiku Street, Xicheng District, Beijing 100034, China.
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MeSH Terms
Aged, 80 and over
Angiography / methods*
Contrast Media
Middle Aged
Pulmonary Embolism / radiography*,  ultrasonography
Tomography, X-Ray Computed / methods*
Reg. No./Substance:
0/Contrast Media

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