| CT and MR patterns of hypoxic ischemic brain damage following perinatal asphyxia. | |
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MedLine Citation:
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PMID: 11866337 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The objectives were to study the clinical and neurological abnormalities in children with cerebral palsy and to attempt to correlate the signs with radiological abnormalities detected by CT scan and/or MRI of the brain. In a prospective, hospital-based study, 65 children with cerebral palsy were examined neurologically and their perinatal history was reviewed. Their cranial CT scan, and/or magnetic resonance images were studied. The association between the gestational ages, perinatal history, neurological deficits, and the radiological appearances were studied. Of the 24 preterm-born and 41 term-born children, 23 had spastic diplegia; 57 per cent of these children has significant periventricular leucomalacia, which was more common among preterm-born children. Of the 13 children with hemiplegia, 12 had unilateral lesions on neuroimaging. Spastic tetraplegia was associated with extensive, bilateral, diffuse brain damage. Extrapyramidal cerebral palsy was far more common among term-born infants and 80 per cent of these showed significant abnormalities in the basal ganglia region. Ataxic cerebral palsy was an uncommon variety and there was no significant correlation between neurological signs and abnormalities on brain imaging. In conclusion, the radiological findings were closely related to the type of cerebral palsy and the neurological deficit except in the ataxic type. We believe that CT and MRI imaging are helpful in understanding the pathology and the timing of the lesion in cerebral palsy. |
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Authors:
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A Gururaj; L Sztriha; A Dawodu; K R Nath; E Varady; M Nork; D Haas |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of tropical pediatrics Volume: 48 ISSN: 0142-6338 ISO Abbreviation: J. Trop. Pediatr. Publication Date: 2002 Feb |
Date Detail:
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Created Date: 2002-02-27 Completed Date: 2002-03-26 Revised Date: 2006-03-28 |
Medline Journal Info:
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Nlm Unique ID: 8010948 Medline TA: J Trop Pediatr Country: England |
Other Details:
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Languages: eng Pagination: 5-9 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, Faculty of Medicine, Al Ain Hospital, United Arab Emirates. GururajA@uaeu.ac.ae |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Asphyxia Neonatorum
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complications Brain Ischemia / pathology* Cerebral Palsy / etiology, pathology* Humans Hypoxia, Brain / pathology* Infant, Newborn Infant, Premature Magnetic Resonance Imaging* Retrospective Studies Tomography, X-Ray Computed* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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