Document Detail

CT and MR findings in central pontine and extrapontine myelinolysis--a study of two patients.
MedLine Citation:
PMID:  9104064     Owner:  NLM     Status:  MEDLINE    
Central pontine and extrapontine myelinolysis is a distinctive clinical syndrome and has characteristic CT and MR features. We describe two patients who presented with nasopharyngeal carcinoma, severe hyponatremia, and had quick correction of hyponatremia. Low T1 and high T2 signal alterations were seen in the basal ganglia and caudate nuclei in both patients whilst one of them had concommitant ventrolateral thalami and central pontine region involvement. Neurologic recovery was good in one case, and initially seen in the other patient before death resulted from septicaemia. Peripheral enhancement of the basal ganglia and caudate nuclei was seen in one patient, which we believe is a new feature.
E Huin; K P Tan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  37     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-05-19     Completed Date:  1997-05-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  SINGAPORE    
Other Details:
Languages:  eng     Pagination:  622-6     Citation Subset:  IM    
Department of Diagnostic Radiology, Singapore General Hospital, Singapore.
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MeSH Terms
Brain / pathology*,  radiography*
Magnetic Resonance Imaging
Middle Aged
Myelinolysis, Central Pontine / diagnosis*,  radiography
Tomography, X-Ray Computed*

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