Document Detail

The CT and MR evaluation of migrational disorders of the brain. Part II. Schizencephaly, heterotopia and polymicrogyria.
MedLine Citation:
PMID:  2748227     Owner:  NLM     Status:  MEDLINE    
The migrational disorders are a rare group of congenital malformations of the brain. They consist of the following entities - lissencephaly (agyria - pachygyria), pachygyria, schizencephaly, heterotopia and polymicrogyria. We studied 40 children with migrational disorders radiologically with CT and MR. This article (Part II) deals with our patients with schizencephaly, heterotopia and polymicrogyria. These patients presented clinically with a variety of symptoms. The most common were seizures, delayed development, failure to thrive and hydrocephalus. CT and MR both demonstrated the characteristic findings in all of our patients except the polymicrogyria group. The gray matter and cleft abnormalities seen in these disorders were demonstrated with CT and MR. However, MR provided better delineation of these disorders than CT. Because some forms of migrational disorders can be inherited, it is extremely important for the radiologist to understand the characteristic findings for correct diagnosis which is essential for parental counseling.
S E Byrd; R E Osborn; T P Bohan; T P Naidich
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric radiology     Volume:  19     ISSN:  0301-0449     ISO Abbreviation:  Pediatr Radiol     Publication Date:  1989  
Date Detail:
Created Date:  1989-08-16     Completed Date:  1989-08-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  219-22     Citation Subset:  IM    
Department of Radiology, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois.
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MeSH Terms
Brain / abnormalities*,  pathology,  radiography
Child, Preschool
Infant, Newborn
Magnetic Resonance Imaging*
Tomography, X-Ray Computed*

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