| CT, MR, US,18F-FDG PET/CT, and their combined use for the assessment of cervical lymph node metastases in squamous cell carcinoma of the head and neck. | |
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MedLine Citation:
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PMID: 18843493 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this retrospective study was to compare the diagnostic value of four different imaging methods-computed tomography (CT), magnetic resonance (MR) imaging, ultrasonography (US), and (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT-and their combined use for preoperative detection of cervical nodal metastases in head and neck squamous cell carcinoma (SCC). Sixty-seven patients (58 men and 9 women; mean age, 60.1 years) with head and neck SCCs underwent CT, MR, US, and PET/CT before surgery. First, each study was reviewed separately for the presence of nodal metastases. Then, the value of combined images was assessed based on a confidence rating score for each modality assigned by observers. These results were verified, on a level-by-level basis, with histopathologic findings. Histopathologic examination revealed nodal metastases in 74 of 402 nodal levels. The sensitivity, specificity, and accuracy were 77.0%, 99.4%, and 95.3% for CT and MR; 78.4%, 98.5%, and 94.8% for US; and 81.1%, 98.2%, and 95.0% for PET/CT, respectively. The comparison of these modalities showed no statistically significant difference among them (p > 0.05). The combination of CT, MR, US, and PET/CT improved sensitivity (86.5%), without loss of specificity (99.4%) and accuracy (97.0%), although the difference failed to reach statistical significance. |
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Authors:
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Dae Young Yoon; Hee Sung Hwang; Suk Ki Chang; Young-Soo Rho; Hwoe Young Ahn; Jin Hwan Kim; In Jae Lee |
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Publication Detail:
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Type: Journal Article Date: 2008-10-09 |
Journal Detail:
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Title: European radiology Volume: 19 ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-02-05 Completed Date: 2009-08-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 634-42 Citation Subset: IM |
Affiliation:
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Department of Radiology, Kangdong Seong-Sim Hospital, Hallym University College of Medicine, Kangdong-Gu, Seoul, Republic of Korea. evee0914@chollian.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Carcinoma, Squamous Cell / diagnosis*, pathology, radiography Female Fluorodeoxyglucose F18 / diagnostic use* Head and Neck Neoplasms / diagnosis*, pathology, radiography Humans Lymphatic Metastasis / diagnosis*, pathology, radiography Magnetic Resonance Imaging / methods* Male Middle Aged Positron-Emission Tomography / methods* Tomography, X-Ray Computed / methods* Ultrasonography / methods* |
| Chemical | |
Reg. No./Substance:
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63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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