Document Detail

CT Fluoroscopy-guided Percutaneous Osteoplasty for the Treatment of Osteolytic Lung Cancer Bone Metastases to the Spine and Pelvis.
MedLine Citation:
PMID:  22920977     Owner:  NLM     Status:  In-Data-Review    
PURPOSE: To retrospectively assess the results of computed tomographic (CT) fluoroscopy-guided percutaneous osteoplasty (PO) of osteolytic lung cancer bone metastases, focusing on pain reduction, improved quality of life, and patient mobility.
MATERIALS AND METHODS: Over a 43-month interval, 92 patients with lung cancer bone metastases underwent PO, including vertebroplasty and acetabuloplasty. A total of 261 lesions of the vertebral column and 22 lesions of the pelvis, ilium, and femur were treated with the use of CT fluoroscopic guidance. Clinical outcomes were assessed, including pain, quality of life, and mobility, 24 hours before, 24 hours after, and 1 and 3 months after osteoplasty.
RESULTS: Pain reduction and improved quality of life and patient mobility were observed in most patients. Visual analog scale and Karnofsky Performance Scale scores changed significantly (P < .05), from 6.1 ± 1.4 and 69.3 ± 5.5 at 24 hours before osteoplasty, respectively, to 3.5 ± 1.2 and 75.2 ± 5.4 at 24 hours after the procedure, 3.3 ± 1.2 and 76.5 ± 5.8 at 1 month, and 2.9 ± 1.5 and 79.6 ± 5.8 at 3 months after PO. Mobility scale score, Frankel classification of spinal cord injury, and Harris hip score also changed significantly (P < .05) after osteoplasty. No major complications occurred.
CONCLUSIONS: PO was shown to be a highly effective and safe palliative therapy to reduce pain and improve quality of life and patient mobility, not only in vertebral metastases, but also in pelvic, iliac, and femoral metastases.
Zhiyu Wang; Yan Zhen; Chungen Wu; Hongtao Li; Yumei Yang; Zan Shen; Hui Zhao; Yang Yao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of vascular and interventional radiology : JVIR     Volume:  23     ISSN:  1535-7732     ISO Abbreviation:  J Vasc Interv Radiol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9203369     Medline TA:  J Vasc Interv Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1135-42     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 SIR. Published by Elsevier Inc. All rights reserved.
Department of Internal Oncology, Sixth People's Hospital, Shanghai JiaoTong University, 600 Yishan Rd., Shanghai 200233, China.
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