Document Detail


CSF 5-hydroxyindoleacetic acid levels in suicidal schizophrenic patients.
MedLine Citation:
PMID:  6199986     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Concentrations of 5-hydroxyindoleacetic acid (5-HIAA) in the lumbar CSF were measured in a group of suicidal schizophrenic patients and in a matched group of nonsuicidal schizophrenic patients. The suicidal group had a significantly lower level. This finding is consistent with reports of low levels of CSF 5-HIAA in suicidal patients with other psychiatric diagnoses and suggests that low CSF 5-HIAA may be a generalized marker of aggressive behavior against the self and others.
Authors:
P T Ninan; D P van Kammen; M Scheinin; M Linnoila; W E Bunney; F K Goodwin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of psychiatry     Volume:  141     ISSN:  0002-953X     ISO Abbreviation:  Am J Psychiatry     Publication Date:  1984 Apr 
Date Detail:
Created Date:  1984-04-24     Completed Date:  1984-04-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370512     Medline TA:  Am J Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  566-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aggression / psychology
Female
Humans
Hydroxyindoleacetic Acid / cerebrospinal fluid*
Male
Mental Disorders / cerebrospinal fluid,  psychology
Schizophrenia / cerebrospinal fluid*
Schizophrenic Psychology*
Suicide / psychology*
Chemical
Reg. No./Substance:
54-16-0/Hydroxyindoleacetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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