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CRP and micro-albumin: New markers of cardiovascular risk in type 2 diabetes.
MedLine Citation:
PMID:  21571249     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
INTRODUCTION: Type 2 diabetes is a chronic disease associated to the presence of multiple risk factors. Among recently studied factors we cite PCR and micro-albumin. OBJECTIVE: In the present study we intend to determine the correlation between urine albumin excretion rate, CRP levels and type of vascular complications in type 2 diabetes. PATIENTS AND METHODS: We recruited 48 type 2 diabetic subjects subdivided into three groups according to the type of vascular complications (GI: type 2 diabetics without complications, GII: type 2 diabetics with microvascular complications and GIII: type 2 diabetics with macrovascular complications). RESULTS: We found a significant elevated levels of CRP and micro-albumin (P<0.05) when we compared diabetics with vascular complications to those without any complications. Diabetics with macrovascular complications have the highest levels of CRP and micro-albumin. Significant positive correlation was found between CRP and micro-albumin levels in a total group of diabetics (r=0.32; P<0.05). CONCLUSION: The determination of CRP and microalbumin levels represents an interest in the screening of cardiovascular disease in type 2 diabetics.
Authors:
M El Oudi; Z Aouni; H Ouertani; C Mazigh; B Nsiri; B Zidi; S Machghoul
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-20
Journal Detail:
Title:  Annales de cardiologie et d'angeiologie     Volume:  -     ISSN:  1768-3181     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-5-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0142167     Medline TA:  Ann Cardiol Angeiol (Paris)     Country:  -    
Other Details:
Languages:  FRE     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Masson SAS. All rights reserved.
Affiliation:
Laboratoire de biochimie, hôpital militaire principal d'instruction, 1008 Montfleury, Tunis, Tunisie.
Vernacular Title:
CRP et micro-albuminurie : nouveaux marqueurs du risque cardiovasculaire chez les diabétiques de type 2.
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